DNA microarray analysis can provide a wealth of new information about genes involved in different aspects of nodule development and function. In future, we plan to increase the number of genes represented on our microarrays, and to use these to profile changes in gene expression during normal nodule development and during development of nodules on Lotus mutants affected in nodule development or function. We will also use microarrays to monitor gene expression in nodules of wild-type plants infected with different mutants of the microsymbiont, Mesorhizobium loti. This should provide deeper insight into the interaction of the two genomes of these important symbionts.
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